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Clinical Research

Clinical research determines the safety and effectiveness of medications, devices, diagnostic products, surgical techniques and treatment regimens. Clinical research can be conducted for prevention, treatment, diagnosis or for relieving symptoms of a disease, such as cancer.


Obermair A, Brennan DJ, Baxter E, Armes JE, Gebski V, Janda M. Surgical safety and personal costs in morbidly obese, multimorbid patients diagnosed with early-stage endometrial cancer having a hysterectomy. Gynecol Oncol Res Pract. 2016 Feb 9;3:1.

Obermair A, Youlden D, Baade P, Janda M. Do breast cancer survivors benefit from prophylactic removal of uterus and ovaries? A population-based data linkage replication study. Asia Pac J Clin Oncol. 2016 May 27. 

Baker J, Janda M, Graves N, Bauer J, Banks M, Garrett A, Chetty N, Crandon AJ, Land R, Nascimento M, Nicklin JL, Perrin LC, Obermair A. Quality of life after early enteral feeding versus standard care for proven or suspected advanced epithelial ovarian cancer: Results from a randomised trial. Gynecol Oncol. 2015;137(3):516-22. 

Brennan DJ, Hackethal A, Mann KP, Mutz-Dehbalaie I, Fiegl H, Marth C, Obermair ASerum HE4 detects recurrent endometrial cancer in patients undergoing routine clinical surveillance. BMC Cancer. 2015;15:33. 

Baker J, Janda M, Gebski V, Forder P, Hogg R, Manolitsas T, Obermair A. Lower preoperative quality of life increases postoperative risk of adverse events in women with endometrial cancer: results from the LACE trial. Gynecol Oncol. 2015; 137(1):102-5. 

Hackethal ABrennan DRao ALand RObermair A et al. Consideration for safe and effective gynaecological laparoscopy in the obese patient. Arch Gynecol Obstet. 2015;292(1):135-41.

Tan YY, Spurdle AB, Obermair A. Knowledge, attitudes and referral patterns of lynch syndrome: a survey of clinicians in Australia. J Pers Med. 2014;4(2):218-44.

Beesley VL, Rowlands IJ, Hayes SC, Janda M, O'Rourke P, Marquart L, Quinn MA, Spurdle AB, Obermair A et al. Incidence, risk factors and estimates of a woman's risk of developing secondary lower limb lymphedema and lymphedema-specific supportive care needs in women treated for endometrial cancer. Gynecol Oncol. 2015;136(1):87-93. 

Anuradha S, Webb PM, Blomfield P, Brand AH, Friedlander M, Leung Y, Obermair A, et al. Survival of Australian women with invasive epithelial ovarian cancer: a population-based study. Med J Aust. 2014;201(5):283-8. 

Hawkes AL, Quinn M, Gebski V, Armes J, Brennan D, Janda M; feMME Trial Committee, Obermair A. Improving treatment for obese women with early stage cancer of the uterus: rationale and design of the levonorgestrel intrauterine device ± metformin ± weight loss in endometrial cancer (feMME) trial. Contemp Clin Trials. 2014;39(1):14-21. 

See a full list of Professor Obermair's Clinical Research Publications

Translational Research

Translational research aims to "translate" findings into real world medical practice and in turn provide meaningful health outcomes.

Obermair H, Janda M, Obermair A. Real-world surgical outcomes of a gelatin-hemostatic matrix in women requiring a hysterectomy: A matched case-control study. Acta Obstet Gynecol Scand. 2016 May 20 [Epub ahead of print].

Khan S,...Australian Ovarian Cancer Study Group,... et al. MicroRNA related polymorphisms and breast cancer risk. PLoS One. 2014;9(11):e109973. 

Hedditch EL,...Australian Ovarian Cancer Study Group,... et al. ABCA transporter gene expression and poor outcome in epithelial ovarian cancer. J Natl Cancer Inst. 2014;106(7).

Gao B,...Australian Ovarian Cancer Study Group,... et al. Paclitaxel sensitivity in relation to ABCB1 expression, efflux and single nucleotide polymorphisms in ovarian cancer. Sci Rep. 2014;4:4669. 

Dong Y, Loessner D, Irving-Rodgers H, Obermair A, et al. Metastasis of ovarian cancer is mediated by kallikrein related peptidases. Clin Exp Metastasis. 2014;31(1):135-47. 

See a full list of Professor Obermair's Translational Research Publications

Tumour Angiogenesis

Mayerhofer K, Lozanov P, Bodner K, Bodner-Adler B, Obermair A, et al. Ki-67 and vascular endothelial growth factor expression in uterine leiomyosarcoma. Gynecol Oncol. 2004;92:175-9.

Stimpfl M, Tong D, Fasching B, Schuster E, Obermair A, et al. Vascular endothelial growth factor splice variants and their prognostic value in breast and ovarian cancer. Clin Cancer Res. 2002;8:2253-9.

Bachtiary B, Selzer E, Knocke TH, Poetter R, Obermair A. Serum VEGF levels in patients undergoing primary radiotherapy for cervical cancer: impact on progression-free survival. Cancer Lett. 2002;179(2):197-203.

See a full list of Professor Obermair's Tumor Angiogenesis Publications

Other Areas of Research

Kusters I, Williams M, Obermair A, Janda M. Women with self-reported lower-limb lymphedema after treatment for gynecological cancers: are they more likely to self-report psychosocial symptoms and less likely to use services? J Community Support Oncol. 2015;13(2):55-61. 

Covens A, Köhler C, Nam JH, Naumann RW, Obermair A, Querleu D. Cost-Efficiency of Robotic Surgery. Int J Gynecol Cancer. 2016;26(6):992-3. 

Rowlands IJ, Beesley VL, Janda M, Hayes SC, Obermair A, et al. Quality of life of women with lower limb swelling or lymphedema 3-5 years following endometrial cancer. Gynecol Oncol. 2014;133(2):314-8. 

Obermair A. Is surgical literature relevant? Int J Gynecol Cancer. 2010;20(8):1300.

Hammond I, Taylor J, Obermair A, McMenamin P. The anatomy of complications workshop: an educational strategy to improve the training and performance of fellows in gynecologic oncology. Gynecol Oncol. 2004;94:769-73.

Janda M, Stanek C, Newman B, Obermair A, Trimmel M. Impact of videotaped information on frequency and confidence of breast self-examination. Breast Cancer Res Treat. 2002;73(3):37-43.

Umek WH, Laml T, Stutterecker D, Obermair A, et al. The Urethra During Pelvic Floor Contraction: Observations on Three-Dimensional Ultrasound. Obstet Gynecol. 2002;100(4):796-800.

Schindl M, Birner P, Obermair A, et al. Increased microvessel density in adenomyosis uteri. Fertil Steril 2001;75:131-135.

Hefler L, Obermair A, et al. Vascular endothelial growth factor serum levels in pregnancy and preeclampsia. Acto Obstet Gynecol Scand 2000;79:77-78.

Kurz CHernandez E, Obermair A, et al. Controversies in the management of endometrial cancer. Obstet Gynecol Int. July 2010. Article ID 894587.

Salzer H, Arbeiter K, Obermair A, et al. L-Carnitin-Betamethason Kombinationstherapie versus alleiniger Betamethasontherapie als Prophylaxe des Atemnotsyndroms. Z Geburtsh Perinat. 1993;197:215-219. [German]

Aichberger L, Boldizsar B, Herczeg S, Obermair A, et al. Die vaginosonografische Beobachtung von Uteruskontraktionen beim Embryotransfer und ihre Relevanz im Hinblick auf den Behandlungserfolg; Geburtshilfe und Frauenheilkunde 1991; 51:27-30. [German].

Obermair A. Die Erstellung einer gynkologisch-onkologischen Patientendatei fr die Nachsorge; Wiener Klin. Wochenschrift. 1991;103:371-373. [German].

Seifert M, Adler A, Obermair A, et al. Mglichkeiten und Ziele der Tumornachsorge beim Mammakarzinom. Gynkol Geburtsh Rundsch. 1991;31:309-311. [German].

Reviews and Book Chapters

Hernandez E, Obermair A, Hoskins PJ, Magrina JF, McLellan R. Controversies in the management of endometrial cancer. Obstet Gynecol Int. 2010;2010. pii: 894587. Epub 2010 Aug 19.

Obermair A. Angiogenese und Prognose beim Mammakarzinom. In: Prognostische und therapierelevante Faktoren beim Mammakarzinom. Ergebnisse einer Konsensuskonferenz. S. Classen, H. Graeff, F. Jnicke, H. Sauer, W. Wilmanns (Hrsg.). Excerpta Oncologica Vol 6, pp 101-109. Novartis Pharma Verlag, Nrnberg 1997. [German]

Obermair A, Preyer O, Leodolter S. Angiogenese in Gynkologie und Geburtshilfe. Wien Klin Woschr. 1999;111:262-277.

Obermair A, Preyer O, Leodolter S. Tumor angiogenesis and its relation to prognosis in epithelial ovarian cancer. CME Journal of Gynecologic Oncology. 1999;4:169-177.

Obermair A, Preyer O, Bachtiary B. Angiogenesis in cervical cancer. CME Journal of Gynecologic Oncology. 2001;6:184-191.